Table 1.
The 25 responsive p53-related gene sets and their ranks of P-values in association analysis
| Responsive p53 gene sets | Rank of gene set | Rank of gene set | Ranks improved |
|---|---|---|---|
| (Uncorrected) | (DECO-sqrt) | ||
| P21_MIDDLE_DN | 396 | 184 | 212 |
| HBX_HEP_UP | 407 | 248 | 159 |
| DNMT1_KO_UP | 241 | 135 | 106 |
| BRCA1_SW480_UP | 296 | 210 | 86 |
| MMS_HUMAN_LYMPH_HIGH_24HRS_DN | 268 | 184 | 84 |
| LIZUKA_G2_GR_G3 | 251 | 222 | 29 |
| P53_SIGNALING | 60 | 36 | 24 |
| OXSTRESS_BREASTCA_UP | 56 | 36 | 20 |
| HSA04115_P53_SIGNALING_PATHWAY | 17 | 1 | 16 |
| HBX_NL_UP | 305 | 291 | 14 |
| BLEO_HUMAN_LYMPH_HIGH_24HRS_UP | 28 | 22 | 6 |
| ZMPSTE24_KO_DN | 78 | 75 | 3 |
| KANNAN_P53_UP | 1 | 1 | 0 |
| P53PATHWAY | 1 | 1 | 0 |
| P53HYPOXIAPATHWAY | 1 | 1 | 0 |
| BLEO_HUMAN_LYMPH_HIGH_4HRS_UP | 1 | 1 | 0 |
| P53GENES_ALL | 1 | 1 | 0 |
| STRESS_P53_SPECIFIC_UP | 1 | 1 | 0 |
| MMS_HUMAN_LYMPH_HIGH_24HRS_UP | 1 | 1 | 0 |
| HASLINGER_B_CLL_11Q23 | 63 | 68 | −5 |
| SHEPARD_NEG_REG_OF_CELL_PROLIFERATION | 51 | 75 | −24 |
| FSH_HUMAN_GRANULOSA_UP | 86 | 121 | −35 |
| HASLINGER_B_CLL_12 | 32 | 80 | −48 |
| SHEPARD_POS_REG_OF_CELL_PROLIFERATION | 177 | 239 | −62 |
| SHEPARD_CRASH_AND_BURN_MUT_VS_WT_UP | 195 | 285 | −90 |