FIG. 1.
NO S-nitrosylates multiple proteins in neurodegenerative diseases. NO S-nitrosylates Parkin and peroxiredoxin 2 (PRX2) in PD (shown in blue); protein-disulfide isomerase (PDI) in PD and AD (shown in green); glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in PD and HD (shown in red); matrix metalloproteinase-9 (MMP-9) in stroke (shown in yellow); and heat-shock protein 90 (HSP90) in AD (shown in pink). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article at www.liebertonline.com/ars).