Figure 5. AAV5-IL-10 induced neuronal expression of IL-10 in the PVN.
(a) IL-10 mRNA levels in the PVN at 28 days following microinjections of AAV5-IL-10, AAV5-GFP or PBS. * P<0.05 vs. GFP or PBS group. † P<0.05 vs. GFP or PBS groups. (b) Representative fluorescence micrographs showing IL10- and NeuN- immunoreactivity in the PVN following AAV5-CBA-IL10 microinjection. The right panel shows the merged images of IL10 and NeuN. Bar = 50 um.
