Figure 5.

Confirmation of NP-Apt conjugation. The A10 PSMA aptamer (Apt) was incubated with PLGA-b-PEG NP in the absence (-) or presence (+) of EDC and the reactions were resolved on a 10% TBE-Urea PAGE directly, or after washing to remove any unconjugated Apt, The bands corresponding to the A10 PSMA Apt and NP-Apt are indicated by arrows. Nucleic acid molecular weight marker (MW) is shown on left,