Figure 1. Small RNAs in Stem Cell Populations.

Mammalian stem cells include embryonic stem cells derived from the inner cell mass of the blastocyst and adult stem cells of the somatic tissues and germline. Embryonic germ cells derived by ex vivo culture of primordial germ cells and embryonal carcinoma cells isolated from teratocarcinomas display similar hallmarks of stem cell pluripotency. Additionally, cancer stem cells are proposed to arise from oncogenic events in adult stem cells.