Table 3.
Differential expression of cell surface markers between HSCs, EPCs, and MSCs. Markers may vary between species; mouse markers are shown because it is the most widely studied animal model. One of the most important distinctions between the groups is that while HSCs are CD34+ and CD45+, MSCs are CD34− and CD45−. CD117 is also known as c-kit.
| HSC | EPC | MSC | |||
|---|---|---|---|---|---|
| Human | Mouse | Human | Mouse | Human | Mouse |
| CD34+ | CD117+ | CD34+ | CD31+/dim | CD90+ | CD90+ |
| CD117+ | CD150+ | CD31+ | VE-cadherin+ | CD157+ | CD44+ |
| CD90+ | Sca-1+ | VE-cadherin+ | Stro-1+ | CD29+ | |
| CD243+ | VEGFR2+ | CD10+ | CD49e+ | ||
| CD133+ | E-selectin+ | CD105+ | |||
| CD45+ | CD202+ | CD71+ | |||
| ?AC133+ | |||||
| CD38− | CD48/CD41− | CD14− | CD45− | CD45− | |
| Lineage & minus; | Lineage & minus; | CD15− | CD11b− | CD34− | CD11b− |