Table 2.
C2 domain similarity compared to corresponding C2 domains from human dysferlin (Type 1) and otoferlin (Type 2).
| Type | Ferlin | C2A | C2B | C2C | C2D | C2DE | C2E | C2F |
|---|---|---|---|---|---|---|---|---|
| 1 | FER1L1_Tadh | 37.1 | 71.4 | 65 | 61 | 72 | 79 | 76.9 |
| 1 | FER1L3_Tadh | 47 | 69.4 | 62.7 | 59.1 | 49.3 | 80 | 51.4 |
| 1 | FER1L1_Nvec | 44.5 | 68.1 | 55.6 | 78 | 76.2 | ||
| 1 | FER1L1_Ccap | 68.7 | 60 | 75 | 75 | 80.8 | ||
| 1 | FER1L1_Lgig | 70.4 | 68.1 | 67 | 52.1 | 76 | 76.9 | |
| 1 | FER1L1_Sman | 66.3 | 55.8 | 59.6 | 73 | 79.2 | ||
| 1 | FER_Cele | 34.6 | 41.8 | 66 | 49.3 | |||
| 1 | FER1L1_Bmal | 30.6 | 54.3 | 49.5 | 65.3 | 60.6 | ||
| 2 | FER1L2_Tadh | 73.3 | 64.9 | 66.1 | 87 | 72.5 | ||
| 2 | FER1L2_Nvec | 78.1 | 72.7 | 85.7 | 69.7 | 53.4 | 89 | 78.6 |
| 2 | FER1L2_Ccap | 56.4 | 64.2 | 71 | 78.6 | |||
| 2 | FER1L2_Lgig | 85.9 | 89.3 | 77.1 | 92 | 90.1 | ||
| 2 | FER1L2_Sman | 26.8 | 57.5 | 39.3 | 75 | 70.2 | ||
| 2 | FER1L1_Phum | 87.9 | 87.5 | 76.1 | 89 | 90.8 | ||
| 2 | Misfire_Dmel | 52.3 | 37.9 | 40 | 66 | |||
Key: The C2DE domain from FER1L2_Nvec was compared to dysferlin C2DE since otoferlin does not contain this corresponding C2 domain. Blank spaces indicate C2 domains not detected by SMART.