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. Author manuscript; available in PMC: 2010 Aug 16.
Published in final edited form as: Annu Rev Immunol. 2008;26:421–452. doi: 10.1146/annurev.immunol.26.021607.090326

Table 3.

Receptors and signaling molecules in MCP-1 production pathway

MTECs

  • Response to TLR-2 and TLR-4 stimulation

  • MCP-1 production requires NF-κB activation but not p38 and JNK MAPKs
Mesothelial cells

  • Response to TLR-2, TLR-3, TLR-4, and TLR-5 stimulation

  • Response to Nod1 stimulation through RIP-2-mediated signaling
Macrophages

  • Response to TLR-1, TLR-2, TLR-3, TLR-4, and TLR-9 stimulation

  • No response to Nod1 stimulation

  • MCP-1 production following L. monocytogenes infection is MyD88-independent
Monocytes

  • MCP-1 production following M. tuberculosis infection requires NF-κB, ERK, and p38 MAPK signaling
HeLa cells

  • MCP-1 production following M. tuberculosis infection requires NF-κB, ERK, and p38 MAPK signaling