FIGURE 2.
Remodeling response of a representative uniaxially loaded engineered tissue construct (ETC) with no switch in boundary conditions. (A) Phase contrast micrograph of the ETC at 0 hr. Scale bar, 200 μm. Inset histogram shows distribution of cell orientation in this image (θ = 10.8°, r = 0.12). (B) Corresponding image and histogram of the same tissue at 24 hrs (θ = −5.6°, r = 0.77), and (C) at 72 hrs of incubation (θ = −4.0°, r = 0.88). (D) Mean angle, θ, and mean vector length, r, versus incubation time obtained for the same tissue construct combining data from four images at each time point.