Skip to main content
. Author manuscript; available in PMC: 2010 Aug 11.
Published in final edited form as: Arch Intern Med. 2010 May 10;170(9):791–802. doi: 10.1001/archinternmed.2010.63

Table 6.

Odds ratios and 95% CIs of Pancreatic Cancer according to Baseline Anthropometric Factors by Gender, the PanScan Consortium, Females

Characteristic Cases Controls OR (95% CI)

1064 1086 Model 1a Model 2b Model 3c Model 4d Model 5e
BMI, kg/m2, cohort- and gender specific quartiles
    Q1 249 280 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
    Q2 249 267 1.07 (0.83-1.36) 1.06 (0.82-1.36) 1.11 (0.84-1.48) 1.07 (0.82-1.39) 1.08 (0.79-1.47)
    Q3 266 275 1.13 (0.89-1.44) 1.08 (0.85-1.39) 1.24 (0.94-1.64) 1.10 (0.85-1.43) 1.16 (0.85-1.57)
    Q4 300 264 1.34 (1.05-1.70) 1.19 (0.93-1.53) 1.37 (1.03-1.81) 1.39 (1.08-1.80) 1.52 (1.11-2.10)
P trend 0.01 0.17 0.02 0.008 0.007

BMI, kg/m2, categories
    Underweight (<18.5 kg/m2) 14 20 0.75 (0.37-1.51) 0.72 (0.35-1.48) 0.65 (0.29-1.44) 0.68 (0.29-1.55) 0.45 (0.16-1.29)
    Normal (≥18.5 and <25.0 kg/m2) 433 500 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
    Overweight (≥25.0 and <30.0 kg/m2) 365 333 1.31 (1.07-1.60) 1.27 (1.03-1.55) 1.40 (1.12-1.76) 1.30 (1.05-1.61) 1.34 (1.04-1.72)
    Obese (≥30.0 kg/m2) 173 174 1.19 (0.93-1.54) 1.12 (0.87-1.46) 1.23 (0.92-1.64) 1.25 (0.96-1.63) 1.29 (0.93-1.79)
    Severely obese (≥35.0) 79 59 1.61 (1.12-2.33) 1.29 (0.88-1.89) 1.50 (0.98-2.30) 1.65 (1.13-2.40) 1.98 (1.17-3.36)
P trend 0.003 0.08 0.01 0.002 0.001

Weight, kg, cohort- and gender specific quartiles
    Q1 265 285 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
    Q2 235 276 0.92 (0.72-1.18) 0.93 (0.73-1.20) 0.89 (0.67-1.18) 0.94 (0.72-1.21) 0.86 (0.62-1.18)
    Q3 279 269 1.14 (0.90-1.46) 1.12 (0.87-1.43) 1.16 (0.88-1.52) 1.18 (0.91-1.52) 1.14 (0.84-1.54)
    Q4 285 256 1.23 (0.96-1.56) 1.12 (0.87-1.44) 1.27 (0.96-1.68) 1.24 (0.96-1.61) 1.34 (0.98-1.84)
P trend 0.03 0.22 0.03 0.03 0.02

Height, cm, cohort- and gender specific quartiles
    Q1 338 330 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
    Q2 245 255 0.91 (0.72-1.16) 0.89 (0.70-1.14) 0.89 (0.67-1.17) 0.89 (0.69-1.15) 0.79 (0.57-1.09)
    Q3 248 265 0.89 (0.71-1.13) 0.92 (0.72-1.17) 0.95 (0.73-1.24) 0.89 (0.69-1.14) 0.98 (0.73-1.32)
    Q4 233 236 0.92 (0.72-1.17) 0.95 (0.74-1.21) 0.95 (0.72-1.25) 0.89 (0.69-1.16) 0.85 (0.63-1.16)
P trend 0.45 0.69 0.80 0.38 0.52

Waist circumference, cohort- and gender specific quartilesf
    Q1 147 162 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
    Q2 117 143 0.89 (0.64-1.25) 0.92 (0.66-1.30) 0.81 (0.56-1.16) 0.85 (0.60-1.22) 0.77 (0.51-1.14)
    Q3 153 148 1.14 (0.83-1.58) 1.14 (0.82-1.58) 1.08 (0.76-1.54) 1.12 (0.80-1.57) 1.14 (0.77-1.68)
    Q4 173 147 1.31 (0.95-1.80) 1.26 (0.91-1.75) 1.28 (0.91-1.80) 1.24 (0.88-1.73) 1.17 (0. 79-1.73)
P trend 0.04 0.09 0.06 0.10 0.19

Waist-to-hip ratio, cohort- and gender specific quartilesf
    Q1 119 143 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
    Q2 120 131 1.14 (0.80-1.63) 1.21 (0.84-1.74) 1.15 (0.78-1.68) 1.20 (0.83-1.75) 1.20 (0.80-1.82)
    Q3 126 154 0.96 (0.67-1.36) 0.94 (0.66-1.34) 0.96 (0.66-1.39) 0.92 (0.63-1.33) 0.97 (0.64-1.47)
    Q4 163 109 1.87 (1.31-2.69) 1.85 (1.27-2.69) 1.77 (1.20-2.61) 1.95 (1.33-2.86) 1.61 (1.03-2.50)
P trend 0.003 0.008 0.01 0.005 0.11
a

Adjusted for cohort, age (categorical), anthropometry source (self-reported, measured), and smoking (never, former, current).

b

Adjusted for cohort, age (categorical), anthropometry source (self-reported, measured), smoking (never, former, current), and diabetes history (no, yes).

c

Adjusted for cohort, age (categorical), anthropometry source, smoking, and excluding the first 2 years of follow-up.

d

Adjusted for cohort, age (categorical), anthropometry source, and excluding current and former smokers.

e

Adjusted for cohort, age (categorical), anthropometry source, and excluding the first 2 years of follow-up, current and former smokers, and people with diabetes.

f

Models for waist circumference and waist-to-hip ratio were additionally adjusted for height.

NOTE: Statistically significant results are in bold.