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. Author manuscript; available in PMC: 2010 Aug 10.
Published in final edited form as: Mamm Genome. 2009 Jun 10;20(9-10):654–663. doi: 10.1007/s00335-009-9192-7

Fig. 5.

Fig. 5

Differential expression of GH/IGF-1 axis components in P21 biallelic and null males. SYBR Green-based quantification of genes involved in GH/IGF-1 axis function, normalized to Rpl32, and plotted relative to expression level in nulls. Numbers of animals are indicated; error bars represent standard error. Transcription factors responsible for each gene are indicated below. Overexpression in biallelics is seen for the following transcripts: Sst (p = 0.0161), GHRH (p = 0.0458), GH (p = 0.0037), and Prl-r (p = 0.0184), and IGF-1 (p = 0.001) which was included as a control. No significant difference was observed in IGFBP3 level