Figure 3. Activation by notification of rewards and losses.
Coronal and axial images are right-left reversed per radiological convention, with the Talairach coordinate of the image plane indicated. Group-wise activations survive False Discovery Rate correction to q < .05. Notification of rewards (contrasted with notification of failure to win reward) activated the ventral striatum (VS) in both controls (A) and in adolescents with externalizing disorders (AED) (B), with a significant voxelwise group difference in activation by this contrast depicted in (D). Reward notification also activated mesial frontal cortex in both in controls (D) and in AED (E), with significant voxel-wise group differences depicted in (F). Notification of all losses (versus notification of successful loss avoidance) activated right anterior insula in both controls (G) and in AED (H).