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. 2010 May 20;31(8):1434–1441. doi: 10.1093/carcin/bgq098

Fig. 2.

Fig. 2.

SI polyp formation. (a) Small intestinal polyp (marker −200 μM). (b and c) Polyp number was greater in mid or distal than proximal ApcMin/+ SI (P = 0.017). Polyp load was greater in mid than in proximal or distal ApcMin/+ SI (P < 0.001). Treatment by 1α,25-(OH)2 D3 or analogues significantly inhibited polyp number and polyp load in all ApcMin/+ regions (P < 0.001). 1α,25-(OH)2 D3 had a significantly greater inhibitory effect on polyp number than QW or BTW at all SI regions (P < 0.01). Statistically significant interactive effects of treatment and small intestinal region were observed for polyp number (P < 0.001). 1α,25-(OH)2 D3 and BTW had maximal inhibitory effects on polyp number and polyp load in the mid SI, whereas QW showed maximal inhibition of polyp load only in the mid SI.