Fig. 2.
The effect of ethanol on MAO B mRNA level and catalytic activity. Rats were fed with an ethanol diet or control diet for 28 days, and a the rat MAO B mRNA levels were determined by quantitative real-time RT-PCR, and b the rat MAO B catalytic activity was determined by enzymatic activity assay using the prefrontal cortex. Data represent the mean ± S.D. of three independent experiments with 10 rats (n = 10) in each group. Controls were the untreated group, which were taken as 1 in a. The MAO B mRNA level and catalytic activity are significantly increased in the ethanol-treated group as compared to the untreated control group (* P < 0.01 and # P < 0.02)