TABLE 1.
PUTATIVE ANTIOXIDANT RESPONSE ELEMENTS OR ANTIOXIDANT RESPONSE ELEMENT–LIKE SEQUENCES DETERMINED IN THE MOUSE PPARG PROMOTER BY BIOINFORMATIC ANALYSIS
| Location | Sequence | PWM* | MS† | Orientation |
|---|---|---|---|---|
| −9306/-9286 | tcaggGTGAGggaGCTagctt | 7.3 | 0.825 | FW‡ |
| −8688/-8668 | tctcaATAATacaGCAtctga | 9.0 | 0.774 | FW |
| −8211/-8191 | tgtgtTGCttgGTGATggctc | 6.8 | 0.788 | CF§ |
| −7660/-7640 | caaggGGCtatGTCATggtgg | 13.3 | 0.901 | CF |
| −6928/-6908 | tcaaaTTGACagaGAAacatg | 8.8 | 0.788 | FW |
| −6043/-6023 | tttgcTGCtgcATCACagtta | 12.1 | 0.869 | CF |
| −4638/-4618 | aagagAGCtatATCAGggtcc | 7.5 | 0.825 | CF |
| −2150/-2130 | atgaaATGAGtgaGCTacatt | 9.1 | 0.856 | FW |
| −784/-764 | tcattGTGACataGCActtat | 14.2 | 0.91 | FW |
*
Position weight matrix score.
†
Matrix similarity score.
‡
Forward.
§
Complimentary forward.
Antioxidant response element core-like sequences (5′-RTKAYnnnGCR-3′; R = A or G, K = G or T, Y = C or T, n = A, C, G, or T) are underlined, and mismatch sequences relative to the core are italicized.