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. 2010 Jul 19;120(8):2715–2730. doi: 10.1172/JCI41824

Figure 2. ARv567es enhances ARfl activity in benign prostate epithelial cells.

Figure 2

(A) P69 SV40T immortalized, nontransformed human prostate epithelial cells transfected with ARv567es demonstrated a marked increase in ARfl protein compared with P69 pcDNA empty vector control cells (P69 pc). (B) ARR3-Luc reporter assay of P69 pcDNA control cells versus P69 ARv567es cells, showing increased transcriptional activity basally and in response to DHT, consistent with increased ARfl expression and ARv567es expression (mean ± SEM). #P < 0.05, P69 ARv567es compared with P69 pc control cells in the absence of androgen; *P < 0.01, P69 ARv567es compared with P69 pc cells with and without DHT added.