Figure 1.
Linkage disequilibrium (LD) map of the gene HAO2. The map was generated using the program HaploView and genotype data of 58 SNPs from the 30 trios of the HapMap CEPH. The white bar on top shows the physical position of the SNPs. Each square represents the correlation of two SNPs, and the shades of red indicate the strength of the correlation ranging from no correlation (white) to strong correlation (red). Blue squares represent uncertain situations. The correlation analysis identifies three blocks of LD highlighted by the black outlines. The variability of each of the three blocks can be captured by a small number of tag SNPs: for example the larger block of 23 SNPs on the right can be described by six SNPs.