Skip to main content
. Author manuscript; available in PMC: 2010 Jun 30.
Published in final edited form as: Cell Stem Cell. 2007 Sep 6;1(3):245–247. doi: 10.1016/j.stem.2007.08.008

Figure 2. Cells Induced in the Absence of Drug Selection Are Pluripotent.

Figure 2

(A) Teratomas generated by clones 2K-1 (middle) and 2K-3 (right) were comparable in weight and appearance to those generated by control ES cells (left).

(B) Teratomas generated by both clones were similar to control ES cells (data not shown) and contained derivatives of all three germ layers, such as cartilage and gut epithelium (left panel) and neural tissue (right panel).

(C) High-contribution chimera resulting from the injection of clone 2K-1 into blastocysts. Similar results were obtained for clone 2K-3.

(D) Sections showing extensive contribution of injected cells to brain (m, midbrain), heart (v, ventricular myocardium), and gut endoderm (i, intestinal epithelium).