Table 1.
Metabolic pathways altered by diet in the humanized mouse gut microbiome*.
| KEGG Pathways Enriched on LF/PP diet | Cyanoamino acid metabolism |
| Glycosaminoglycan degradation | |
| Glycosphingolipid biosynthesis - ganglioseries | |
| N-Glycan degradation | |
| Nucleotide sugars metabolism | |
| Other ion-coupled transporters | |
| Pentose and glucuronate interconversions | |
| Phenylpropanoid biosynthesis | |
| Sphingolipid metabolism | |
| Starch and sucrose metabolism | |
|
KEGG Pathways Enriched on Western diet |
ABC transporters |
| Phosphotransferase system (PTS) | |
| Transporters |
Based on a bootstrap analysis of gut microbiome datasets from humanized mice fed the LF/PP diet (7–35 dpc) or the Western diet (29–35dpc; CI=0.95, 10,000 samples; inclusion criterion, pathways must be found at ≥0.6% relative abundance in at least two samples) dpc, days post colonization with a human fecal sample