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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Am J Transplant. 2009 Nov 4;10(1):40–46. doi: 10.1111/j.1600-6143.2009.02859.x

Table 1.

Banff score of mouse liver grafts□

Control anti-B7-H1mAb p-value*
Portal triad inflammation 2.0±0.0 2.8±0.4 < 0.05
Venous inflammation 1.4±0.5 2.6±0.5 < 0.05
Bile duct inflammation 0.8±0.4 2.0±0.7 < 0.05
Necrosis 0.0±0.0 1.4±0.5 < 0.005
Total 4.2±0.8 7.4±1.7 < 0.005
□

The severity was graded from mild to severe according to the Banff scoring system for acute rejection, which assigns the cellular infiltration of portal triads, bile duct inflammation, and endothelial inflammation scores ranging from 1–3 thus indicating; 1, minimal changes; 2, moderate changes; or 3, severe changes. Additional findings not included in the Banff scoring system were also examined. The extent of necrosis was scored as the percentage of parenchymal involvement (0, no necrosis present; 1, <25% of the total parenchyma involved; 2, 25–50% of total parenchyma involved; 3, 50–75% of the total parenchyma involved and 4, >75% of total parenchyma involved).

*

Significant difference was calculated at day 8 using Mann–Whitney test between the control and anti-B7-H1mAb administration groups.