Table 2.
Genomic loci with statistically significant copy number variation between early and late onset colorectal cancers.
| Chromosome | Band | Mbps from pter | Size (Mbps) | p-value (average) |
|---|---|---|---|---|
| Gain | ||||
| 2 | q35 | 217.2 | 3.2 | 0.03 |
| 5* | q13.2 | 69.5 | 0.3 | 0.03 |
| 10 | q21.3-22.1 | 70.9 | 2.4 | 0.02 |
| 10 | q22.3 | 79.5 | 1.5 | 0.01 |
| 19 | q13.2-13.31 | 44.6 | 3.9 | 0.02 |
| Loss | ||||
| 1 | p31.3 | 61.5 | 0.3 | 0.02 |
| 1 | q21.1 | 145.02 | 0.6 | 0.02 |
| 2 | q21.2 | 132.78 | 0.1 | 0.02 |
| 4 | p16.1 | 8.88 | 0.7 | 0.02 |
| 4 | p14 | 39.6 | 1.0 | 0.05 |
| 4 | q21.3-22.1 | 88.02 | 0.4 | 0.02 |
| 4 | q22.1-28.2 | 88.44 | 41.1 | 0.04 |
| 4 | q28.2-28.3 | 129.96 | 2.0 | 0.05 |
| 4 | q28.3 | 132.96 | 0.3 | 0.03 |
| 10 | p11.1 | 38.94 | 0.1 | 0.03 |
| 19 | p12 | 20.52 | 0.3 | 0.03 |
*Aberration is significantly more often present in the late onset than the early onset patients.