Figure 4.
DNGR-1+ BDCA3+ DCs display a gene expression profile characteristic of mouse CD8α+ DCs. Normalized expression of DNGR-1, Necl2, CD207, BATF3, IRF8, IRF4, TLR7, TLR9, DAP12, TLR8, and TLR3 mRNA in BDCA3+ DNGR-1+ DCs (DNGR-1+) purified either from CBDCs or from pooled spleens of two to five humanized mice (hu mice). Expression was compared with that of BDCA2+ pDCs purified from the same humanized mouse spleens. Data are representative of two independent experiments. ND, not detectable.
