Table 1.
Number of signature probes and genes for each mouse cell subpopulation (stringent criteria)
| Mammary epithelial cell subsets | Mouse probes |
Unique mouse genes |
Mouse genes with human orthologues |
|---|---|---|---|
| MaSC-enriched | |||
| Upregulated | 2,616 | 1,790 | 1,438 |
| Downregulated | 2,305 | 1,620 | 1,316 |
| Luminal progenitor | |||
| Upregulated | 521 | 373 | 286 |
| Downregulated | 170 | 132 | 111 |
| Mature luminal | |||
| Upregulated | 1,026 | 733 | 569 |
| Downregulated | 1,034 | 740 | 624 |
| Stroma | |||
| Upregulated | 1,933 | 1,273 | 998 |
| Downregulated | 1,264 | 911 | 773 |
Stringent signature probes were chosen by using fold-change > 1.5 and global FDR < 0.05.