TABLE 4. RELATIVE CONDUCTANCE OF VASCULAR GAP JUNCTIONS AND HEMICHANNELS.
| Cx37 | Cx40 | Cx43 | Cx45 | |
|---|---|---|---|---|
| unitary conductance (pS) | ||||
| junction (Vj) | 300, 347 (Reed et al., 1993; Veenstra et al., 1994b; Veenstra et al., 1995) | 142-198 (Beblo and Veenstra, 1997; Veenstra et al., 1995) | 60-120 (Veenstra et al., 1995; Wang and Veenstra, 1997) | 26-37 (Valiunas, 2002; Veenstra et al., 1994a; Veenstra et al., 1995) |
| hemichannel (Vj) | 600* (Banach et al., 2000; Hu et al., 2006) |
300 (Rackauskas et al., 2007) | 220 (Contreras et al., 2003) | 57 (Valiunas, 2002) |
| substate | 63 (Veenstra et al., 1994b) | 30-36 | 30-60 | 23 |
| relative tracer permeability | ||||
| EB or PI | Cx37 = Cx40 | |||
| LY | Cx43 >> Cx40 > Cx45 = Cx40/Cx45 = Cx43/45** > Cx37 (Heyman and Burt, 2008; Rackauskas et al., 2007) | |||
| A350 | Cx45 > Cx40 > Cx43 > Cx37 = Cx37/Cx43 (Weber et al., 2004) | |||
| Cx43 >> Cx40 >> Cx40/45 = Cx43/Cx45 > Cx37 (Heyman and Burt, 2008; Rackauskas et al., 2007) | ||||
| A488 | Cx43 > Cx40 > Cx45 >> Cx37 = Cx37/Cx43 (Weber et al., 2004) | |||
| A594 | Cx43 > Cx45 > Cx40 >> Cx37/Cx43 > Cx37(nd) (Weber et al., 2004) | |||
Abbreviations: predicted hemichannel conductance of Cx37, which has not been demonstrated due to a lack of voltage dependent saturation (Banach et al., 2000; Veenstra et al., 1994b); nd, not demonstrated.