Table 2.
Summary of Antibodies for Immunohistochemistry
| Protein | Function | Marker for | Antibody, manufacturer, titer | Reference |
|---|---|---|---|---|
| CD68 (ED1) | Glycoprotein on lysosomal membrane of myeloid cells | Macrophages, monocytes, weakly peripheral blood granulocytes | Mouse anti-rat CD68, 1:200 (AbD Serotec, Raleigh, NC) | 16 |
| CD163 (ED2) | Cell surface glycoprotein | Microglial cells, resident tissue macrophages, but not monocytes | Mouse anti rat CD163, 1:200 (AbD Serotec, Raleigh, NC) | 17, 18 |
| vWF | Glycoprotein in plasma, endothelium, megakaryocytes | Vascular endothelial cells or megakaryocytes | Rabbit anti human vWF, 1:5000 (Dako, Carpinteria, CA) | 19 |