. Author manuscript; available in PMC: 2010 May 25.

Published in final edited form as: Am J Psychiatry. 2009 Sep 1;166(10):1170–1177. doi: 10.1176/appi.ajp.2009.08121801

TABLE 2. [¹¹C]Raclopride Nondisplaceable Binding Potential at Baseline and Following AMPT Administration.

Striatal Subdivision	Treatment Condition

	Baseline					AMPT

	Healthy Comparison Subjects (N=15)		Cocaine-Dependent Subjects (N=15)		Unpaired t test (p)	Healthy Comparison Subjects (N=15)		Cocaine-Dependent Subjects (N=15)		Unpaired t test (p)

	Mean	SD	Mean	SD		Mean	SD	Mean	SD
Ventral striatum	2.12	0.26	1.88	0.29	0.02	2.37	0.26	1.96	0.38	0.002
Precommissural dorsal caudate	2.25	0.16	2.01	0.34	0.02	2.49	0.19	2.11	0.40	0.002
Precommissural dorsal putamen	2.62	0.26	2.39	0.31	0.04	2.93	0.30	2.51	0.36	0.002
Postcommissural caudate	1.34	0.15	1.31	0.26	0.67	1.54	0.20	1.45	0.30	0.33
Postcommissural putamen	2.59	0.22	2.35	0.34	0.03	2.96	0.25	2.54	0.42	0.002
Striatum	2.30	0.18	2.08	0.28	0.01	2.59	0.20	2.22	0.35	0.001

TABLE 2. [11C]Raclopride Nondisplaceable Binding Potential at Baseline and Following AMPT Administration.