Fig. 2.

PPARγ agonists stimulate PPRE reporter gene transcription. (A) A schematic representation of the PPRE reporter (AOX)3-TK-Luc. (B) HEK293 cells were transfected with (AOX)3-TK-Luc reporter with or without PPARγ or PPARγEA469, and then were incubated with 5 μM of different PPARγ ligands, as indicated. The fold increase in luciferase activities ±S.E.M. was determined.