Table 1.
Summary of the fractional anisotropy versus age in years least-squares fitted results on the 24 fiber tracts along with the standard errors and significant p values
| Fiber tracts fractional anisotropy | y = β0 + β1 × age + β2 × age2 |
|||
|---|---|---|---|---|
| β0 ± SD | β1 ± SD | β2 ± SD | ||
| Association pathways | ||||
| ATP | R | 410.74 ± 9.35* | 1.62 ± 0.63† | −0.030 ± 0.009† |
| 93 (24C, 69A) | L | 408.86 ± 10.93* | 1.45 ± 0.73‡ | −0.030 ± 0.011† |
| AFP | R | 435.46 ± 7.68* | 1.99 ± 0.51* | −0.034 ± 0.007* |
| 98 (25C, 73A) | L | 413.098 ± 9.214* | 2.22 ± 0.61* | −0.036 ± 0.009* |
| AFT | R | 451.76 ± 10.42* | 1.68 ± 0.67† | −0.029 ± 0.009† |
| 69 (16C, 53A) | L | 443.41 ± 10.39* | 2.39 ± 0.67† | −0.037 ± 0.009* |
| IFOF | R | 480.79 ± 9.25* | 1.35 ± 0.62† | −0.025 ± 0.009† |
| 104 (28C, 76A) | L | 485.20 ± 10.39* | 1.50 ± 0.61† | −0.029 ± 0.009* |
| ILF | R | 459.21 ± 8.25* | 2.54 ± 0.56* | −0.040 ± 0.008* |
| 103 (29C, 74A) | L | 480.58 ± 7.75* | 0.93 ± 0.53‡ | −0.020 ± 0.008† |
| UF | R | 408.87 ± 9.52* | 1.75 ± 0.65† | −0.028 ± 0.009† |
| 100 (29C, 71A) | L | 414.76 ± 8.66* | 1.75 ± 0.60† | −0.026 ± 0.009† |
| Projection pathways | ||||
| CST | R | 569.22 ± 10.81* | 0.92 ± 0.76‡ | −0.020 ± 0.011‡ |
| 93 (27C, 66A) | L | 593.35 ± 10.07* | 0.41 ± 0.71‡ | −0.011 ± 0.011‡ |
| Sensory | R | 460.72 ± 10.54* | 1.11 ± 0.71‡ | −0.012 ± 0.010‡ |
| 92 (25C, 67A) | L | 457.93 ± 10.58* | 1.74 ± 0.71† | −0.022 ± 0.010† |
| Commissural (corpus callosum) pathways | ||||
| CC1 (prefrontal) | 562.56 ± 8.90* | 0.613 ± 0.623‡ | −0.028 ± 0.009† | |
| CC2 (anterior frontal) | 521.89 ± 8.56* | 0.62 ± 0.60‡ | −0.020 ± 0.009† | |
| CC3 (superior frontal) | 534.54 ± 8.47* | 1.68 ± 0.59† | −0.024 ± 0.009† | |
| CC4 (posterior frontal) | 527.15 ± 10.69* | 2.85 ± 0.75* | −0.039 ± 0.011* | |
| CC5 (anterior parietal) | 529.78 ± 10.43* | 1.30 ± 0.73‡ | −0.021 ± 0.011* | |
| CC6 (posterior parietal) | 570.02 ± 10.31* | 0.05 ± 0.72‡ | −0.014 ± 0.011‡ | |
| CC7 (temporal) | 569.94 ± 10.47* | −0.02 ± 0.01‡ | −0.017 ± 0.011‡ | |
| CC8 (occipital) | 637.08 ± 8.51* | 0.61 ± 0.60‡ | −0.015 ± 0.009‡ | |
Age at peak (in years) and standard deviation (SD) were computed assuming significant fit model (linear and quadratic) coefficients as detailed in the “Methods”
NA not available as any of the linear or quadratic terms was not significant
p < 0.0001
p < 0.05
p = 0.08