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Ethanol intake (±SEM; gram per kilogram) in PKCε wild-type (+/+; n = 6) and null-mutant (−/−; n = 5) mice after pre-treatment with flumazenil, followed by diazepam 10 min later. * Denotes significant difference between genotypes at the respective dose (Tukey, P < 0.05). + Denotes significant difference from vehicle (0 + 0) within genotype (Tukey, P < 0.05). # Denotes significant difference from 5 mg flumazenil/kg + 10 mg diazepam/kg treatment (Tukey, P < 0.05).
