Table 1.
Umbilical cord blood-derived mononuclear cells (MNC), Lin− and CD34+ purified cells were incubated overnight with Pro-Fe[647] particles. The hematopoietic stem/progenitor cell surface markers CD34 and CD133 were assessed by FACS analysis to determine the percentage of Fe[647] nanoparticle uptake in each progenitor cell population.
| Cell Type | N | Nano+ Total |
CD34+ Total | CD133+ Total | CD34+/Nano+ | CD133+/Nano+ |
|---|---|---|---|---|---|---|
| MNC | 3 | 28.1+/−3 | 7+/−1.4 | 4.4+/−4.5 | 6.2+/−0.8 | 3.5+/−5 |
| Lin− | 7 | 39+/−23.7 | 34.7+/−11.5 | 27.7+/−17 | 8.8+/−3.3 | 5.7+/−2.6 |
| CD34+ | 6 | 37.6+/−15.8 | 90+/−3.6 | 79.4+/−20.1 | 31.8+/−13.9 | 26.7+/−18.3 |