Figure 4. Functional Surfaces of the Bro1 Domain.
(A) Ribbon diagram of Bro1 domain shown in the same perspective as (B)–(D) for reference.
(B) Molecular surface of the Bro1 domain colored according to residue property: green, hydrophobic; blue, basic; red, acidic; white, uncharged polar.
(C) Bro1 domain surface colored according to residue conservation as in Figure 2A.
(D) Bro1 domain surface colored according to electrostatic potential, with blue electropositive and red electronegative.
(E) The same surface as in (D) is rotated by 180° about the x axis to show the opposite side of the boomerang.
(F) Close-up of hydrophobic patch 1.
(G) Close-up of hydrophobic patch 2.
