Figure 1.
Ang II induces NADPH-mediated superoxide generation in hVSMCs. A, NADPH-mediated superoxide production by Ang II (10−7 mol/L) treated cells (24 hours) relative to control cells. Superoxide generation determined at 40 second intervals was plotted over a total period of 40 minutes. Data are representative of 4 separate experiments. B, Time-dependent increase in superoxide production in Ang II–treated cells. Bars represent mean+SEM; n=5 (P<0.01 for all time points compared with control). AUC indicates total area under curve.