Table 3.
Multivariate analysis of transplantation outcomes
| Variable | NRM |
Relapse |
EFS |
OS |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | HR | 95% CI | P | HR | 95% CI | P | |
| Recipient age, y | ||||||||||||
| < 50 | 1 | — | — | — | — | — | — | — | — | 1 | — | — |
| 50-59 | 0.82 | 0.28-2.42 | .72 | — | — | — | — | — | — | 1.01 | 0.51-1.99 | .98 |
| ≥ 60 | 2.23 | 0.75-6.64 | .15 | — | — | — | — | — | — | 1.95 | 0.93-4.10 | .08 |
| Donor age, y | ||||||||||||
| < 43 | 1 | — | — | — | — | — | — | — | — | 1 | — | — |
| ≥ 43 | 2.29 | 0.87-6.01 | .09 | — | — | — | — | — | — | 1.66 | 0.90-3.08 | .1 |
| TNC dose, × 108/kg | ||||||||||||
| < 3.2 | — | — | — | 1 | — | — | 1 | — | — | 1 | — | — |
| 3.2-4.7 | — | — | — | 0.47 | 0.24-0.87 | .017 | 0.62 | 0.36-1.07 | .09 | 0.53 | 0.28-1.02 | .06 |
| > 4.7 | — | — | — | 0.44 | 0.20-0.93 | .031 | 0.59 | 0.31-1.11 | .10 | 0.53 | 0.25-1.14 | .10 |
| Disease status at transplantation | ||||||||||||
| CR | — | — | — | 1 | — | 1 | — | — | — | — | — | |
| Not in CR before alloBMT | — | — | — | 2.94 | 1.53-5.67 | .001 | 1.88 | 1.14-3.09 | .01 | — | — | — |
| Recipient CMV serology | ||||||||||||
| Negative | 1 | — | — | — | — | — | — | — | — | — | — | — |
| Positive | 2.02 | 0.78-5.21 | .14 | — | — | — | — | — | — | — | — | — |
Table reflects only those variables that remained in the final multivariate model.
—indicates not applicable.