Fig. 3.
Lipidomic profiles of epidiymal adipose tissue in CONV-R compared with GF mice. A: PLS/DA of adipose lipids from GF (n = 9) and CONV-R (n = 5) mice after a 4 h fast. Scores for latent variable LV1 and sample are depicted. Regression coefficients and VIP scores for the top ranked lipids are listed in supplementary Table V. B–C: Absolute concentrations of the most abundant phosphatidylcholines (PC) and triglycerides (TG) in adipose tissue from GF and CONV-R mice. For a complete list of microbially altered adipose lipids, see supplementary Table VI. Data are expressed as mean values ± SEM. * P < 0.05 compared with GF mice.