TABLE 2.
Pearson correlations between adipose tissue mRNA expression of SIRT1 and PGC-1α with adipose tissue mRNA expression of genes regulating mitochondrial function (n = 81)
| SIRT1 | PGC-1α | |
|---|---|---|
| PGC-1β | r = 0.358 | r = 0.152 |
| P = 0.001 | P = 0.179 | |
| NRF1 | r = 0.286 | r = 0.235 |
| P = 0.010 | P = 0.036 | |
| ERRα | r = 0.339 | r = 0.260 |
| P = 0.002 | P = 0.021 | |
| TFAM | r = 0.379 | r = 0.213 |
| P = 0.001 | P = 0.059 | |
| NDUFA2 | r = 0.392 | r = 0.273 |
| P = 3.5 × 10−4 | P = 0.015 | |
| CYCS | r = 0.263 | r = 0.159 |
| P = 0.019 | P = 0.161 | |
| COX4I1 | r = 0.332 | r = 0.262 |
| P = 0.003 | P = 0.020 | |
| ATP5G1 | r = 0.248 | r = 0.196 |
| P = 0.027 | P = 0.084 | |
| SOD1 | r = 0.460 | r = 0.348 |
| P = 2.0 × 10−5 | P = 0.002 | |
| SOD2 | r = −0.046 | r = −0.009 |
| P = 0.689 | P = 0.940 | |
| CAT | r = 0.350 | r = 0.422 |
| P = 0.002 | P = 1.3 × 10−4 |
Expression of all genes was normalized to RPL0 expression. ATP5G1, ATP synthase, H + transporting, mitochondrial F0 complex, subunit C1; CAT, catalase; COX4I1, cytochrome c oxidase subunit IV isoform 1; CYCS, cytochrome c, somatic; NDUFA2, NADH dehydrogenase (ubiquinone) 1 α subcomplex 2; SOD1, superoxide dismutase 1, soluble; SOD2, superoxide dismutase 2, mitochondrial.