Table 2.
Phytanic, pristanic acid and total fatty acid levels in mice supplemented with phytol.
| 0.5% phytol supplementation a | ||
|---|---|---|
| Tissue levels of phytanic acid (expressed as % of total fatty acids) | Pex7 neo/neo | Pex7 neo/+ |
| Brain (n=1) | 3.46 | 0.04 |
| Heart (n=1) | 9.26 | 0.75 |
| Liver (n=1) | 25.19 | 0.45 |
| Plasma (n=10) | 10.41 (±8.70) b range 3–30 | 0.69 (±0.33) range 0.2–1.2 |
| Plasma levels of phytanic, pristanic and saturated fatty acids (uM) | ||
| Phytanic acid (n=10) | 733.27 (±753.76) range 224–2827 | 73.76 (±36.10) range 26–140 |
| Pristanic acid (n=10) | 2.8 (± 3.0) | 4.1 (± 3.5) |
| Total saturated FA (n=4) | 1473.21(± 230.38) | 1940.26 (±300.52) |
a
Dietary phytol is converted endogenously to phytanic acid
b
mean and STD, p < 0.05 except for pristanic acid p=0.71 (sample means compared by student T test, parameters were 2 tailed, unequal variance)