Fig. 3.
CD2 and F-actin accumulate at the activating NKIS more readily than does perforin. (A) Conjugation of YTS-CD2/GFP cells with 721.221 over time (⋄) was calculated as a percentage of total YTS-CD2/GFP cells present. (B) The accumulation of F-actin (▴), CD2/GFP (▪), and perforin (•) at the IS of YTS-CD2/GFP cells conjugated with 721.221 cells was evaluated for each time point (except time 0 due to the insignificant number of conjugates found). Individual points are the mean of four to eight experiments ± SD.