Table A2.
Prognostic Factors by Survival Type
| Variable | Survival Data |
|||
|---|---|---|---|---|
| All Patients |
Patients With Mutation Data |
|||
| Hazard Ratio | P > χ2 | Hazard Ratio | P > χ2 | |
| Progression-free survival | ||||
| Female sex | 0.829 | .0021 | 0.740 | .0008 |
| WHO performance status | 1.173 | < .0001 | 1.234 | .0004 |
| Hemoglobin, g/dL | 0.938 | .0001 | 0.936 | .0062 |
| Neutrophils, 109/L | 1.054 | < .0001 | 1.054 | < .0001 |
| Site of origin by overall test | — | .0054 | — | .0477 |
| Other sites v stomach | 1.129 | .1017 | 0.856 | .1588 |
| Small bowel v stomach | 1.259 | .0012 | 1.119 | .2856 |
| Mutations | < .0001 | |||
| KIT exon 9 | 2.206 | < .0001 | ||
| Other | 2.659 | < .0001 | ||
| Wild type | 1.717 | < .0001 | ||
| Overall survival | ||||
| Age, years | 1.013 | < .0001 | 1.011 | .0150 |
| Female sex | 0.777 | .0026 | 0.677 | .0016 |
| WHO performance status | 1.289 | < .0001 | 1.519 | < .0001 |
| Tumor diameter, cm | 1.002 | .0018 | 1.003 | .0001 |
| Neutrophils, 109/L | 1.062 | < .0001 | 1.049 | .0060 |
| Albumin | 0.758 | .0002 | 0.717 | .0008 |
| Prior chemotherapy | 1.326 | .0014 | NS | |
| Mutations | — | < .0001 | ||
| KIT exon 9 | 2.187 | < .0001 | ||
| Other | 1.612 | .0692 | ||
| Wild type | 1.755 | .0010 | ||
Abbreviation: NS, not significant.