Table 1.
Absolute amounts of elastin produced in cultures treated with LOX-1, LOX-2 and within non-additive controls at the end of 21 days. Data shown here represents the average of n = 3/case.
| Culture Condition | Tropoelastin, mg | Matrix elastin, mg | Total elastin/DNA, mg/mg | |
|---|---|---|---|---|
| Soluble fraction, mg | Crosslinked Insoluble fraction, mg | |||
| Control | 46.5 ± 5 | 16.3 ± 2.2 | 2.3 ± 0.3 | 21.017 ± 2445 |
| LOX-1 | 29 ± 8.3 | 32.5 ± 4.7 | 5.8 ± 0.01 | 14953 ± 2897 |
| LOX-2 | 50.5 ± 0.8 | 34.4 ± 0.5 | 7.1 ± 0.2 | 24111 ± 423 |