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Liver tumors form in the absence of Mst1 and Mst2. (A) Livers from 6-month-old TM-injected wild-type and mutant mice. Two of the mutant livers with tumor nodules are shown. (B) H&E staining of liver sections from the liver samples in A. Boxed regions are shown in the lower panel in higher magnification. Both hepatocyte carcinoma (HCC) and chonlangiocyte carcinoma (CC) were observed. Multilayered epithelial cells are indicated by arrows.
