TABLE 1. Summary of pathology groups.
Based on clinical presentation, pathology, and flow cytometry, we grouped 26 samples into five major classes. P1, normal resting B cells; P2, normal activated B cells; P3, marginal cases; P4, transitional cases; P5, aggressive cases (aggressive 8, 9, 19, 20, 21, 22, 23; transitional 13, 14, 15, 16, 17; marginal 5, 6, 7, 10, 11, 12; activated 2, 25, 26; resting 1, 3, 4, 18, 24)
| Group | n | Description | Splenomegaly | Other pathology | FACS | Ig gene clonality |
|---|---|---|---|---|---|---|
| P1 | 5 | Resting | None | None | Normal resting | Polyclonal |
| P2 | 3 | Activated | None | None | Normal activated | Polyclonal |
| P3 | 6 | Marginal | +/− | +/− | Abnormal | Oligoclonal |
| P4 | 5 | Transitional | + | + | Mixed | Oligoclonal |
| P5 | 7 | Aggressive | +++ | +++ | B-1 clones | Monoclonal |