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. Author manuscript; available in PMC: 2010 Feb 10.
Published in final edited form as: Curr Biol. 2008 May 22;18(12):890. doi: 10.1016/j.cub.2008.05.010

Figure 2. Characterization of RIP-Cre/lacZ Pancreas.

Figure 2

(A) Scheme illustrating β cell-specific activation of lacZ expression in RIP-Cre/lacZ mice.

(B) Frozen pancreas sections from a RIP-Cre/lacZ mouse after Xgal staining shows islet specific labeling.

(C) Immunofluorescence staining of a RIP-Cre/lacZ islet section with antibodies against insulin (red) and β-galactosidase (green) demonstrates exclusive expression of β-galactosidase in insulin-positive β cells. The position of a rare β cell not expressing β-galactosidase is highlighted by white arrows.