Table 2.
Clinical characteristics of 114 patients who received EBV-specific CTLs after transplantation
| Characteristic | CTL recipients |
|---|---|
| Age at transplantation, y [mean (range)] | 8.4 (0.5-38) |
| Male:female | 69:45 |
| Diagnosis | |
| Acute lymphoblastic leukemia | 29 |
| Acute myeloid leukemia | 33 |
| Myelodysplasia | 11 |
| Acute undifferentiated leukemia | 1 |
| Chronic myeloid leukemia | 12 |
| Hodgkin disease | 1 |
| Non-Hodgkin lymphoma | 3 |
| Aplastic anemia | 1 |
| Paroxysmal nocturnal hemoglobinuria | 2 |
| Histiocytic disorders | 3 |
| Hurler syndrome | 2 |
| X-linked lymphoproliferative disease | 6 |
| Wiskott-Aldrich syndrome | 5 |
| Osteogenesis imperfecta | 3 |
| Common immunodeficiency | 2 |
| Type of transplantation | |
| Unrelated donor | |
| 10/10 match | 3 |
| 9/10 match | 4 |
| 6/6 match | 63 |
| 5/6 match | 30 |
| Family member | |
| Syngeneic | 1 |
| 5/6 match | 6 |
| 4/6 match | 4 |
| 3/6 match | 3 |
| HSC product | |
| Marrow | 108 |
| PBSC | 6 |
EBV indicates Epstein-Barr virus; CTL, cytotoxic T lymphocyte; HSC, hematopoietic stem cell; and PBSC, peripheral blood stem cell.