Fig. 8.
Correlation between mRNA ratios and protein levels of differentially expressed proteins. A, scatter plots of protein expression ratios from proteomics data against mRNA abundance ratios from microarray data. B, a pictorial comparison of significantly changed protein ratios against the corresponding mRNA ratio with functional clustering based on the biological process category of Gene Ontology. Red and green colors represent an increase or decrease in -fold change, respectively. C, gene module-based correlation analysis between the proteomics and microarray data. After partitioning genes with altered mRNA or protein expression separately into small function categories, or gene modules, we compared GO contents between mRNA data and protein data in response to T2D and found that the results were highly coordinate.