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. Author manuscript; available in PMC: 2010 Jan 18.
Published in final edited form as: Development. 2007 Oct 10;134(22):4119–4130. doi: 10.1242/dev.009290

Fig. 3. SHP-2 activity is required for pharyngeal mesoderm.

Fig. 3

(A) Schematic of tissues and rudimentary organ structures in Xenopus tissue explants. (B) Cardiac explants isolated and cultured in DMSO or NSC-87877 (NSC) beginning at stage 22. In situ hybridization performed on explants with Tbx1, Fgf8, at stages 22, 26, 29 and 33. (C) Whole-mount in situ hybridization of Endocut, Endodermin, Sox2, Ami and Xmsr at stage 37; whole embryos and cardiac explants treated with DMSO (control) or NSC-87877, as indicated.