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. 2009 Aug 23;302(1):47–55. doi: 10.1007/s00403-009-0989-8

Table 4.

Presence of CD31 and α-smooth muscle actin during fetal development and in adult skin

First trimester Second trimester Adult skin
13–14 weeks 16–18 weeks 19–20 weeks 21–22 weeks
Dermis Pap Ret Pap Ret Pap Ret Pap Ret
CD31 ++ + ++ + ++ + ++ ++ ++
α-SMA ++ + ++ + ++ + ++ ++ ++

Pap Papillary dermis, Ret reticular dermis