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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Neurobiol Aging. 2008 Mar 4;30(11):1865–1876. doi: 10.1016/j.neurobiolaging.2008.01.002

Figure 5.

Figure 5

Cellular localization, gene expression and protein level of ferroportin (Fpn) in the retinas of young and old mice. A–B. Cellular localization of Fpn in the retinas of young (A) and old mice (B). Fpn localizes in the NFL (white arrows), GCL (arrows) and INL in the retinas. Fpn protein appears increased in the aged retinas. Note that there is increased intensity in the NFL and GCL. C. Western blot shows Fpn protein increased significantly in the aged retinas compared to young retinas. Densitometric measurements confirm a significant increase in Fpn in aged retinas (*p < 0.05, n=3). D. Graph showing no significant difference of relative expression of Fpn mRNA between the young and aged retinas (p > 0.05, n=6). Scale bar: 20 μm.