Fig. 7.
Cell-autonomous regulation of VSX2, MITF and PAX2 expression by Lhx2. (A-P) Single-scan confocal images of LHX2, VSX2, MITF, PAX2 and PAX6 expression in mouse E10.5 optic neuroepithelium mosaic for Lhx2. LHX2-negative cells are outlined (dashed line). Images in each row are from the same section and the merged panels show the overlap of LHX2 with each marker. DAPI panels show that areas lacking LHX2 expression do contain cells. In contrast to VSX2, MITF and PAX2, PAX6 expression persisted in LHX2-negative cells. Scale bar: 40 μm.