Figure 5. Adoptive Transfer of a Limited Number of gp33-Specific CD8+ T Cells Does Not Significantly Alter the Overall Response to gp33, gp276, or np396 during the Immune Response to LCMV.
Primary CTL activity of splenocytes from uninfected B6.PL mice that received 105 P14 cells (open circles) and day 8 LCMV-infected mice (filled symbols) that received no P14 cells (squares), 103 P14 cells (diamonds), 105 P14 cells (triangles), or 106 P14 cells (crosses) 1 day prior to infection. Lysis was determined on day 8 of infection by 51Cr-release assay using EL4 targets without additional peptide (A) and EL4 pulsed with gp33 (B), gp276 (C), or np396 (D) peptides. Data are presented as the average specific lysis of targets by effectors from three individual mice per group, with standard deviation indicated by error bars (some of which fall within the symbols). Two repetitions of the experiment yielded similar results.
