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. Author manuscript; available in PMC: 2009 Nov 12.
Published in final edited form as: Immunity. 1998 Feb;8(2):167–175. doi: 10.1016/s1074-7613(00)80469-0

Figure 4. GP33-Specific TCR-Transgenic CD8+ T Cells Expand Dramatically during LCMV Infection.

Figure 4

Control B6.PL mice (A and C) or B6.PL mice that had received 105 P14 spleen cells (~3 × 104 transgenic CD8+ cells) 1 day earlier (B and D) were infected with LCMV. After 8 days spleens were removed and assayed for CD4 versus CD8 staining (A and B) and donor (CD8+Thy1.2+) CTL content (C and D). The numbers beside the gating boxes in (A) and (B) indicate the percentage of live gated cells; in (C) and (D) the numbers indicate the number of Thy1.2+ donor cells as a percentage of CD8+ cells. Results are from representative individual mice from groups of three. In uninfected chime-ric mice the donor cells were less than 0.5% of CD8+ cells (data not shown). d8, day 8.